OUTER MEMBRANE PROTEIN A CONSERVATION AMONG ORIENTIA TSUTSUGAMUSHI ISOLATES SUGGESTS ITS POTENTIAL AS A PROTECTIVE ANTIGEN AND DIAGNOSTIC TARGET

Outer Membrane Protein A Conservation among Orientia tsutsugamushi Isolates Suggests Its Potential as a Protective Antigen and Diagnostic Target

Scrub typhus threatens one billion people in the Asia-Pacific area and cases have emerged outside this region.It is caused by infection with any of the multitude of strains of the bacterium Orientia tsutsugamushi.A vaccine that Masks affords heterologous protection and a commercially-available molecular diagnostic assay are lacking.Herein, we deter

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Real-Time Monitoring and Step-by-Step Guidance for Transapical Mitral Valve Edge-to-Edge Repair Using Transesophageal Echocardiography

MitraClip edge-to-edge (E2E) repair system is the only transcatheter device recommended in the current guidelines for treating mitral regurgitation (MR).The percutaneous femoral venous transseptal access of MitraClip requires a complex steerable delivery system and may thus be technically complex to optimally position and deploy the clip onto the m

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